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Investigator Spotlight: Ruth O’Regan MD

Ruth O'Regan, MD

This month, Hoosier Cancer Research Network features our member institution University of Rochester Medical Center – Wilmot Cancer Institute and Ruth O’Regan, MD, the Charles A. Dewey Professor and Chair of Medicine at the University of Rochester Medical Center’s School of Medicine and Dentistry.

Dr. O’Regan is a medical oncologist with more than 25 years of experience in academic medicine. Her research interests are significantly focused on identifying mechanisms of resistance to breast cancer therapies, specifically endocrine-resistant and triple-negative breast cancers.

She has authored or co-authored more than 100 peer-reviewed publications that have appeared in leading oncology, biology, surgery and pathology medical journals, and is deeply committed to the leadership of multidisciplinary clinical, teaching, and research teams.

Dr. O’Regan previously served as division Chief of Hematology, Medical Oncology and Palliative Care in the Department of Medicine and as Deputy Director at the Carbone Cancer Center at the University of Wisconsin School of Medicine and Public Health. She also served as Chief Scientific Officer of the Big Ten Cancer Research Consortium and Vice Chair of the National Comprehensive Cancer Network Board of Directors.

Educational Background:

  • Medical School: University College, Dublin, Ireland
  • Residency: Medical College of Wisconsin and Northwestern University, Internal Medicine
  • Fellowship: Northwestern University, Feinberg School of Medicine, Hematology/Oncology

Three facts about Dr. O’Regan:

  • She loves to travel.
  • She enjoys playing tennis.
  • She is an avid Green Bay Packers fan.


About Hoosier Cancer Research Network 

Hoosier Cancer Research Network (formerly known as Hoosier Oncology Group) conducts innovative cancer research in collaboration with academic and community physicians and scientists across the United States. The organization provides comprehensive clinical trial management and support, from conception through publication. Created in 1984 as a program of the Walther Cancer Institute, Hoosier Cancer Research Network became an independent nonprofit clinical research organization in 2007. Since its founding, Hoosier Cancer Research Network has conducted more than 230 trials in a variety of cancer types and supportive care, resulting in more than 350 publications. More than 9,000 subjects have participated in Hoosier Cancer Research Network clinical trials.