network member

Maryland

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Currently Enrolling

HCRN-BSK22-562

Observational basket trial to predict response to immune checkpoint inhibitors across solid tumors using a live tumor diagnostic platform (CYBRID-02)

Cancer areas:Basket

AdventHealth Orlando

CARTI

John Theurer Cancer Center at Hackensack Meridian Health

Meritus Center for Clinical Research / John R. Marsh Cancer Center

Salinas Valley Health

University of Louisville / James Graham Brown Cancer Center

University of North Carolina Lineberger Comprehensive Cancer Center

University of South Florida

University of Wisconsin Carbone Cancer Center

See clinicaltrials.gov

Currently Enrolling

HCRN-GU16-243

PhAse I/II StuDy of Modern ImmunotherApy in BCG-RelaPsing UroThelial Carcinoma of the BLADDER – (ADAPT-BLADDER) HCRN GU16-243

Noah M. Hahn

Cancer areas:Bladder Urothelial Carcinoma

Columbia University Irving Medical Center

Fox Chase Cancer Center

Fred & Pamela Buffett Cancer Center

Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine

University of Iowa Holden Comprehensive Cancer Center

See clinicaltrials.gov

Currently Enrolling

HCRN-GU20-436

NePtune: A Phase 2 Study of Neoadjuvant PARP Inhibition followed by Radical Prostatectomy in Patients with Unfavorable Intermediate-Risk or High-Risk Prostate Cancer with BRCA1/2 Gene Alterations

Cancer areas:Prostate

Columbia University Irving Medical Center

Memorial Sloan Kettering Cancer Center

Moores Cancer Center at UC San Diego Health

Penn Medicine Abramson Cancer Center

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

See clinicaltrials.gov

Currently Enrolling

TBCRC047

Innovative Combination Immunotherapy for Metastatic Triple Negative Breast Cancer (TNBC): A Multicenter, Multi-Arm Translational Breast Cancer Research Consortium Study

Hope Rugo

Cancer areas:Breast

Dana-Farber Cancer Institute

Duke Cancer Institute

Georgetown Lombardi Comprehensive Cancer Center

Mayo Clinic

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

The University of Chicago Medicine Comprehensive Cancer Center

UC San Francisco

University of Alabama at Birmingham Comprehensive Cancer Center

University of North Carolina Lineberger Comprehensive Cancer Center

Vanderbilt-Ingram Cancer Center

See clinicaltrials.gov

Enrollment Closed

BTCRC-HN17-111

Phase II Trial of Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma: Big Ten Cancer Research Consortium BTCRC-HN17-111

Manish Patel

Cancer areas:Head and Neck

Masonic Cancer Center, University of Minnesota

Robert H. Lurie Comprehensive Cancer Center of Northwestern University

University of Illinois Cancer Center

University of Iowa Holden Comprehensive Cancer Center

University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center

University of Michigan Rogel Cancer Center

University of Wisconsin Carbone Cancer Center

See clinicaltrials.gov

Enrollment Closed

HCRN-GU16-287

Randomized phase 2 trial of gemcitabine + carboplatin + nivolumab versus gemcitabine + oxaliplatin + nivolumab in cisplatin-ineligible patients with metastatic urothelial cancer

Matthew D. Galsky

Cancer areas:Bladder Urothelial Carcinoma

Huntsman Cancer Institute at the University of Utah

Icahn School of Medicine at Mount Sinai

Rutgers Cancer Institute of New Jersey

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Vanderbilt-Ingram Cancer Center

See clinicaltrials.gov

Enrollment Closed

BTCRC-LUN18-363

A Phase II Study of Chemo-Immunotherapy Followed by Durvalumab (MEDI4736) and Ceralasertib (AZD6738) in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Big Ten Cancer Research Consortium BTCRC-LUN18-363

Muhammad Furqan

Cancer areas:Lung

Indiana University Melvin and Bren Simon Comprehensive Cancer Center

The Ohio State University

University of Illinois Cancer Center

University of Iowa Holden Comprehensive Cancer Center

University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center

See clinicaltrials.gov