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Texas

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Currently Enrolling

HCRN-GU23-626

Hispanic/Latino and non-Hispanic BlAck patients treated with niRaparib and abiraterone acetate plus prednisone for Metastatic hOrmone sensitive prostate cancer with deleterious homologous recombinatioN repair alterations: a phase II, open label studY (HARMONY)  
Cancer areas:Prostate
UT Southwestern Harold C. Simmons Comprehensive Cancer Center
Currently Enrolling

HCRN-BRE21-516

BRIDGET: Secondary BRain metastases prevention after Isolated intracranial progression on Trastuzumab/Pertuzumab or T-DM1 in patients with aDvanced human epidermal Growth factor receptor 2+ brEast cancer with the addition of Tucatinib
Cancer areas:Breast
Dana-Farber Cancer Institute
Duke Cancer Institute
MD Anderson Cancer Center
Novant Health Oncology Specialists
Providence Cancer Institute
Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine
The Ohio State University
UC San Francisco
University of Michigan Rogel Cancer Center
Currently Enrolling

HCRN-GU21-517

A Phase 2 Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Cancer (CANOPY)
Cancer areas:Prostate
Moores Cancer Center at UC San Diego Health
The University of Chicago Medicine Comprehensive Cancer Center
University of Wisconsin Carbone Cancer Center
UT Southwestern Harold C. Simmons Comprehensive Cancer Center
Currently Enrolling

HCRN-GU22-587

Advanced Renal Cell Cancer Combination ImmunoThErapy Clinical Trial (ARCITECT)
Cancer areas:Kidney
Beth Israel Deaconess Medical Center
Columbia University Irving Medical Center
Dana-Farber Cancer Institute
Georgetown Lombardi Comprehensive Cancer Center
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
John Theurer Cancer Center at Hackensack Meridian Health
Moores Cancer Center at UC San Diego Health
Penn Medicine Abramson Cancer Center
The Ohio State University
UT Southwestern Harold C. Simmons Comprehensive Cancer Center
Weill Cornell Medicine
Winship Cancer Institute of Emory University
Yale Cancer Center
Enrollment Closed

HCRN-BRE18-334

A Phase II circulating tumor DNA enriched, genomically directed post-neoadjuvant trial for patients with residual triple negative breast cancer (PERSEVERE)
Cancer areas:Breast
Advocate Aurora Research Institute (Illinois)
Aurora Health Care
Froedtert & the Medical College of Wisconsin
Georgetown Lombardi Comprehensive Cancer Center
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Miami Cancer Institute at Baptist Health, Inc.
Novant Health Oncology Specialists
The University of Chicago Medicine Comprehensive Cancer Center
University of Alabama at Birmingham Comprehensive Cancer Center
University of Wisconsin Carbone Cancer Center
UT Health San Antonio MD Anderson Cancer Center
Enrollment Closed

HCRN-GU16-260

Phase II study of front line therapy with nivolumab and salvage nivolumab + ipilimumab in patients with advanced renal cell carcinoma
Cancer areas:Kidney
Beth Israel Deaconess Medical Center
Cleveland Clinic Cancer Center
Columbia University Irving Medical Center
Fox Chase Cancer Center
Georgetown Lombardi Comprehensive Cancer Center
Penn Medicine Abramson Cancer Center
Robert H. Lurie Comprehensive Cancer Center of Northwestern University
University of Illinois Cancer Center
UT Southwestern Harold C. Simmons Comprehensive Cancer Center
Winship Cancer Institute of Emory University
Yale Cancer Center
Enrollment Closed

HCRN-LUN18-335

An Open-Label Randomized Phase II Study of Combining Osimertinib with and without Ramucirumab in TKI-naïve EGFR-mutant Locally Advanced or Metastatic NSCLC
Cancer areas:Lung
MD Anderson Cancer Center
Moffitt Cancer Center
Enrollment Closed

HCRN-MEL17-309

Phase II single-arm multi-center study of adjuvant ipilimumab in combination with nivolumab in subjects with high-risk ocular melanoma
Cancer areas:Melanoma
Columbia University Irving Medical Center
Georgetown Lombardi Comprehensive Cancer Center
MD Anderson Cancer Center
Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine
UC San Francisco
Enrollment Closed

BTCRC-GI20-457

A Phase II study of Atezolizumab and Bevacizumab in Child-Pugh B7 Hepatocellular Carcinoma (The AB7 Trial) Big Ten Cancer Research Consortium BTCRC-GI20-457
Cancer areas:Liver and Bile Duct
DHR Health
Fred & Pamela Buffett Cancer Center
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
New York University Cancer Institute
Rutgers Cancer Institute of New Jersey
University of Illinois Cancer Center
University of Wisconsin Carbone Cancer Center