Investigator Spotlight: Rana R. McKay, MD

This month, Hoosier Cancer Research Network highlights Rana R. McKay, MD, a medical oncologist and researcher at UC San Diego Health. Dr. McKay specializes in treating people with urogenital cancers, including bladder, kidney, prostate, and testicular cancers, and leads a multi-disciplinary prostate cancer clinic. As an associate professor in the Department of Medicine, Dr. McKay […]
Investigator Spotlight: Mylin Torres, MD

This month, Hoosier Cancer Research Network highlights Winship Cancer Institute of Emory University and Mylin Torres, MD, professor in the Department of Radiation Oncology, Emory University School of Medicine. Currently, Dr. Torres serves as co-leader of the Cancer Prevention and Control research program at Winship Cancer Institute while also serving as a radiation oncologist at […]
Investigator Spotlight: Andrew Poklepovic, MD

This month, Hoosier Cancer Research Network features Andrew S. Poklepovic, MD, in our investigator spotlight. Dr. Poklepovic serves as assistant professor in the Division of Hematology, Oncology and Palliative Care at the VCU Massey Cancer Center and is a Harrison Endowed Scholar at the VCU School of Medicine. He is also the medical director for […]
Schneider leads new study to develop personalized therapies in triple negative breast cancer

Reposted with permission by the Indiana University School of Medicine. Indiana University School of Medicine researcher Bryan P. Schneider, MD, is leading a novel nationwide study to better understand how to treat patients with triple-negative breast cancer based on their own unique genetic data. PERSEVERE, also known as HCRN BRE18-334, is a phase 2 clinical […]
Investigator Spotlight: Ruth O’Regan MD

This month, Hoosier Cancer Research Network features our member institution University of Rochester Medical Center – Wilmot Cancer Institute and Ruth O’Regan, MD, the Charles A. Dewey Professor and Chair of Medicine at the University of Rochester Medical Center’s School of Medicine and Dentistry. Dr. O’Regan is a medical oncologist with more than 25 years […]
Phase II study for non-small cell lung cancer with EGFR mutation tests osimertinib with or without ramucirumab

A phase II randomized open-label study for locally advanced or metastatic non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) gene mutation, will test the EGFR inhibitor osimertinib with or without ramucirumab. The study, HCRN LUN18-335, is now open to accrual at The University of Texas MD Anderson Cancer Center in Houston; […]
Study tests induction durvalumab followed by chemoradiation and consolidation durvalumab in stage III NSCLC

A multi-institutional single-arm study led by Rachel Sanborn, MD, of the Earle A. Chiles Research Institute, a division of Providence Cancer Institute, is testing the immunotherapy drug durvalumab followed by chemoradiation and consolidation durvalumab for adults with previously untreated stage III non-small cell lung cancer (NSCLC). The study, HCRN LUN18-357, is currently enrolling participants at […]
Tan joins Kudchadkar, Kuzel in leading HCRN melanoma working group

Hoosier Cancer Research Network’s Melanoma Clinical Trial Working Group recently appointed a new co-chair, Alan Tan, MD, director of GU Medical Oncology and assistant professor in the Department of Internal Medicine, Division of Hematology, Oncology and Cell Therapy at Rush Medical College. Dr. Tan (pictured left) joins current co-chairs Ragini R. Kudchadkar, MD, of Emory […]
McConkey, Gupta named HCRN Correlative Sciences co-chairs

David J. McConkey, PhD (pictured left), professor of urology and oncology at The Johns Hopkins University School of Medicine, and Gaorav P. Gupta, MD, PhD, assistant professor of radiation oncology, biochemistry and biophysics at the University of North Carolina School of Medicine, were recently appointed as co-chairs of Hoosier Cancer Research Network’s Correlative Sciences Clinical […]
Investigator Spotlight: Coral Omene, MD, PhD

This month, Hoosier Cancer Research Network features our member institution Rutgers Cancer Institute of New Jersey and Coral Omene, MD, PhD, medical oncologist at Rutgers Cancer Institute and Assistant Professor of Medicine at Rutgers Robert Wood Johnson Medical School. Research Interests and Expertise: Dr. Omene is a medical oncologist with a passion for women’s health […]
HCRN investigators publish results of advanced colorectal cancer study GI14-186

Researchers participating in GI14-186, a Hoosier Cancer Research Network study for patients with metastatic colorectal cancer (mCRC), recently reported their findings in the journal Cancer Immunology, Immunotherapy. The single-arm phase Ib study, led by researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center, tested the hypothesis that the addition of pembrolizumab to […]
Investigator Spotlight: Hans Hammers, MD, PhD

This month, Hoosier Cancer Research Network features our member institution UT Southwestern Harold C. Simmons Comprehensive Cancer Center in Dallas, Texas, and Hans Hammers, MD, PhD, an associate professor of internal medicine in the Division of Hematology and Oncology at the UT Southwestern Medical School and the first Eugene P. Frenkel, M.D. Scholar in Clinical […]
HCRN study published in npj Breast Cancer journal

Results from a Hoosier Cancer Research Network study in triple negative breast cancer, led by researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center, were recently published in npj Breast Cancer. The purpose of the multi-site, phase II study, BRE09-146, “PARP Inhibition After Preoperative Chemotherapy in Patients with Triple Negative Breast Cancer […]
Gupta, McKay appointed co-chairs of HCRN genitourinary working group

Hoosier Cancer Research Network announces the appointment of Shilpa Gupta, MD, of the Cleveland Clinic, and Rana McKay, MD, of the University of California San Diego, as co-chairs of the organization’s Genitourinary Clinical Trial Working Group. The new co-chairs succeed Noah Hahn, MD, of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Matthew Galsky, […]
HCRN cancer researchers present three studies during ASCO 2021

Three HCRN investigator-initiated clinical trials were highlighted during the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting held virtually June 4-8. Deepak Kilari, MD, (pictured left), associate professor at the Medical College of Wisconsin and a medical oncologist at the MCW Cancer Center, presented a poster (Abstract #TPS4591) on HCRN GU18-343, the phase II […]
Researchers present ongoing HCRN LUN18-335 RAMOSE Study

Hoosier Cancer Research Network investigators presented the ongoing study LUN18-335, RAMOSE: An open-label randomized Phase II study of osimertinib with or without ramucirumab in TKI-naïve EGFR-mutant metastatic non-small cell lung cancer (NSCLC), during the World Conference on Lung Cancer earlier this year. Led by Xiuning Le, MD, PhD, of the University of Texas MD Anderson […]
Investigator Spotlight: David Gallinson, DO

This month, Hoosier Cancer Research Network features our member institution Summit Health Cancer Center in Florham Park, New Jersey, and David Gallinson, DO, a medical oncologist.
UNC researchers present UC-GENOME study at AACR Annual Meeting 2021

Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center, along with colleagues from Fox Chase Cancer Center, Icahn School of Medicine at Mount Sinai, Fred Hutchinson Cancer Research Center at the University of Washington, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The University of Chicago Medicine Comprehensive Cancer Center, Memorial Sloan Kettering […]
Investigator Spotlight: Daniel M. Geynisman, MD

This month, Hoosier Cancer Research Network features our member institution Fox Chase Cancer Center, and Daniel M. Geynisman, MD, associate professor, Hematology/Oncology and a medical oncologist at Fox Chase Cancer Center.
Advanced gastric or GE junction cancer study tests novel serial treatment strategy using immunotherapy, anti-angiogenic therapy, and chemotherapy

Based on encouraging preliminary data, researchers at Mayo Clinic in Rochester, Minn., are leading a randomized multi-site phase II study for adults with metastatic, recurrent, or locally advanced unresectable gastric or gastroesophageal (GE) junction adenocarcinoma that tests a novel serial approach to treating these cancers, using immunotherapy, anti-angiogenic therapy, and chemotherapy. The primary goal of […]
HCRN investigators report on GI17-319 study during AACR Annual Meeting

Hoosier Cancer Research Network investigators presented a poster highlighting GI17-319, a gastric and esophageal adenocarcinoma study, during the AACR Annual Meeting 2021. A single arm, multi-center phase 2 trial of mFolfox6 + trastuzumab + avelumab in first-line, metastatic, HER2-amplified gastric and esophageal adenocarcinomas, GI17-319 examined whether adding the anti-PD-L1 antibody avelumab to the chemotherapy drug […]
Investigator Spotlight: Joshua F. Zeidner, MD

This month, Hoosier Cancer Research Network features our member institution University of North Carolina Lineberger Comprehensive Cancer Center and Joshua F. Zeidner, MD, associate professor of medicine, chief of leukemia research, and associate chief of research, hematology at UNC Lineberger.
Every day counts in clinical trial development, activation

The moment a cancer patient learns about their cancer diagnosis, they begin one of the most important conversations they will have with their doctor. Many patients are fortunate to have a clear treatment plan, tested and proven effective through rigorous clinical trials. For others, often diagnosed in the latter stages of disease progression, standard options […]
HCRN researchers present ADAPT-BLADDER phase I study at Society of Urologic Oncology

Noah M. Hahn, MD, deputy director of Johns Hopkins Greenberg Bladder Cancer Institute and sponsor-investigator of the multi-site Hoosier Cancer Research Network ADAPT-BLADDER study, GU16-243, highlighted the Phase I findings during a poster session at the Society of Urologic Oncology’s 2020 Annual Meeting in December. The phase I portion of the clinical trial was open […]
HCRN receives Sustained Excellence Award during ICC Annual Meeting

Hoosier Cancer Research Network (HCRN) received the Indiana Cancer Consortium (ICC) Sustained Excellence Award during the ICC’s 2021 Annual Meeting on April 21. The award is presented to organizations that have longstanding contributions to the consortium and recent notable achievements. The ICC launched from a shared vision of the Indiana State Department of Health, the […]
Investigator Spotlight: Deepak Kilari, MD

This month, Hoosier Cancer Research Network features our member institution Froedtert & the Medical College of Wisconsin in Milwaukee, Wis., and Deepak Kilari, MD, a medical oncologist with specialization in genitourinary cancers.
Investigator Spotlight: Jian Li Campian, MD, PhD

This month, Hoosier Cancer Research Network features our member institution Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, Mo., and Jian Li Campian, MD, PhD, a medical oncologist with specialization in neuro-oncology and immunotherapy.
Investigator Spotlight: Shilpa Gupta, MD

This month, Hoosier Cancer Research Network features our member institution Cleveland Clinic Cancer Center and medical oncologist Shilpa Gupta, MD. Dr. Gupta is a genitourinary oncologist and the leader of the bladder cancer program at the Cleveland Clinic Taussig Cancer Institute in Cleveland, Ohio. She is also a member and co-chair elect of Hoosier Cancer […]
Investigators present pancreatic, hepatocellular carcinoma studies at GI Cancers Symposium

Hoosier Cancer Research Network investigators recently presented abstracts during the 2021 Gastrointestinal Cancers Symposium. The abstracts included a poster featuring the HCRN GI14-198 study, led by Walid Shaib, MD, of Winship Cancer Institute at Emory University, and a trials in progress poster featuring HCRN GI19-405, led by Aiwu Ruth He, MD, of Georgetown University Lombardi […]
Kim joins El-Rayes, McRee in leading HCRN GI Clinical Trial Working Group

Richard Kim, MD, service chief of Medical Gastrointestinal Oncology and senior member in the Gastrointestinal Oncology Department at Moffitt Cancer Center, has been appointed as a co-chair of the Hoosier Cancer Research Network (HCRN) Gastrointestinal Clinical Trial Working Group. He joins fellow co-chairs Bassel El-Rayes, MD, of Winship Cancer Institute at Emory University, and Autumn […]
Investigator Spotlight: Dwight Owen, MD, MS

This month, Hoosier Cancer Research Network features our member institution The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and medical oncologist Dwight Owen, MD, MS. Dr. Owen is a member of the Translational Therapeutics Program at the OSUCCC – James.
Investigator Spotlight: Nancy B. Davis, MD

This month, Hoosier Cancer Research Network features our member institution Vanderbilt-Ingram Cancer Center (VICC) in Nashville, Tenn., and Nancy B. Davis, MD, associate professor of medicine and VICC senior medical director for Cancer Care Network and Strategy, Division of Hematology/Oncology, Vanderbilt University Medical Center.
IU researchers show rapid disease recurrence more likely in TNBC patients with TP53 mutations

The Hoosier Cancer Research Network multi-center BRE12-158 study on triple-negative breast cancer (TNBC), led by Indiana University Melvin and Bren Simon Comprehensive Cancer Center, was recently presented as a Spotlight Poster Discussion during the 2020 San Antonio Breast Cancer Symposium virtual meeting. The correlative analysis from the study, “A Phase II Randomized Controlled Trial of […]
Cintron joins HCRN as first chief operating officer

Hoosier Cancer Research Network recently welcomed Vivian Cintron, PhD, MBA, as its first chief operating officer. In her new role, she will work closely with HCRN’s executive director, Cyndi Burkhardt, and the management team to support company operations and strengthen relationships with investigators, key opinion leaders, and industry collaborators. Dr. Cintron is a molecular biologist […]
IU oncology nurse, Alesha Arnold joins HCRN Board of Directors

Hoosier Cancer Research Network, a nonprofit cancer research organization based in Indianapolis, recently welcomed Indiana University School of Medicine research nurse Alesha Arnold, RN, as a member of its Board of Directors. Arnold joined the IU School of Medicine in 2008 and supports the Clinical Trials Office at the IU Melvin and Bren Simon Comprehensive […]
Fausel leads HCRN with guidance, grit, and iron

Since Christopher A. Fausel, PharmD, MHA, BCOP, was appointed as Chairman of the Board of Directors for Hoosier Cancer Research Network in July 2013, he has guided HCRN through tremendous growth, two moves, and now – a pandemic. He has also helped HCRN raise more than $23,000 through HCRN’s Reps for Research challenge. From 2014 […]
Fisher Fund helps Indiana University fellows further lung cancer research

Two Indiana University School of Medicine hematology-oncology fellows are digging deep into timely cancer research questions, with research support provided by the George and Sarah Jane Fisher Fund. Melissa Yan, MD, and Nikhil Shukla, MD, are investigating biomarkers that may one day provide more personalized solutions in treating lung cancer. Each award recipient received $6,000 […]
Investigator Spotlight: Ulka Nitin Vaishampayan, MBBS, FAB

This month, Hoosier Cancer Research Network features our member institution, the University of Michigan Rogel Cancer Center, and Ulka Nitin Vaishampayan, MBBS, FAB, director of the phase I program at Rogel Cancer Center and a professor of internal medicine at the University of Michigan Medical School. Dr. Vaishampayan is leading an HCRN multi-institution study that […]
Investigator Spotlight: Benjamin Maughan, MD, PharmD

This month, Hoosier Cancer Research Network features our member, the Huntsman Cancer Institute at the University of Utah and Benjamin Maughan, MD, PharmD, assistant professor in the Division of Medical Oncology at Huntsman Cancer Institute, who specializes in genitourinary cancers. Dr. Maughan is a site principal investigator for the HCRN bladder cancer studies GU16-257, GU16-287, […]
HCRN investigators present bladder cancer study during ESMO Virtual Congress

Hoosier Cancer Research Network investigators recently presented an E-Poster on the HCRN study GU18-343 during the ESMO 2020 Virtual Congress. The multi-center clinical trial, “A Phase 2 Study of Cabozantinib in Combination with Atezolizumab as NeoAdjuvant Treatment for Muscle-Invasive BladdEr Cancer (ABATE),” is led by Deepak Kilari, MD, a medical oncologist and researcher at Froedtert […]
Investigator Spotlight: Christos Kyriakopoulos, MD

This month, Hoosier Cancer Research Network features our member, the University of Wisconsin Carbone Cancer Center, and Christos Kyriakopoulos, MD, associate professor of medicine at the University of Wisconsin School of Medicine and Public Health, and a medical oncologist and researcher at UW Carbone Cancer Center. Research Interests and Expertise Dr. Kyriakopoulos is an institutional […]
LUN14-179 NSCLC study published in Clinical Lung Cancer, ACS journals

The Hoosier Cancer Research Network study, LUN14-179, “A Phase II Trial of Concurrent Chemoradiation With Consolidation Pembrolizumab (MK-3475) for the Treatment of Inoperable or Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC): HCRN LUN14-179,” affirms the effectiveness of consolidation immunotherapy after chemoradiation in adults with unresectable stage IIIA or IIIB non-small cell lung cancer. The […]
Investigator Spotlight: William P. Harris, MD

This month, Hoosier Cancer Research Network features our member Fred Hutchinson Cancer Research Center and William P. Harris, MD, associate professor of medicine for the University of Washington School of Medicine and a medical oncologist at Fred Hutch. Research Interests and Expertise Dr. Harris is a GI medical oncologist with a main research focus on […]
Investigator Spotlight: Naomi Haas, MD

This month, Hoosier Cancer Research Network features our member Penn Medicine Abramson Cancer Center and Naomi Haas, MD, Director of Kidney and Prostate Cancer Clinical Research at Penn Medicine and Associate Professor of Medicine at the Hospital of University of Pennsylvania. Dr. Haas is an international expert in the conduct and design of adjuvant clinical […]
Investigator Spotlight: Michael B. Atkins, MD

This month, Hoosier Cancer Research Network features our member Georgetown Lombardi Comprehensive Cancer Center and Michael B. Atkins, MD, deputy director of the cancer center, William M. Scholl Professor, and vice chair of the Department of Oncology. Dr. Atkins is an international leader in translational and clinical research, with more than 30 years of experience […]
Stringer-Reasor joins Anders in co-chairing HCRN Breast Cancer Working Group

Erica Stringer-Reasor, MD, assistant professor of medicine in the Division of Hematology & Oncology at the University of Alabama at Birmingham (UAB), has been appointed as a co-chair of the Hoosier Cancer Research Network (HCRN) Breast Cancer Clinical Trial Working Group. Dr. Stringer-Reasor joins fellow co-chair Carey K. Anders, MD, a professor of medicine at […]
Phase II small cell lung cancer study tests guadecitabine combined with carboplatin in extensive-stage disease

A phase II study for adults with extensive-stage small cell lung cancer is testing the hypomethylating agent guadecitabine combined with the platinum-based chemotherapy drug carboplatin. The study is open to accrual at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center in Indianapolis, Ind.; IU Health Ball Memorial Cancer Center in Muncie, Ind.; and […]
Durm, Fidler, Gentzler appointed as HCRN Thoracic CTWG co-chairs

Investigators participating in Hoosier Cancer Research Network’s Thoracic Clinical Trial Working Group have named three of their colleagues to serve as co-chairs of the group. The new co-chairs are (pictured from left) Greg Durm, MD, assistant professor of clinical medicine at Indiana University School of Medicine and a researcher at the IU Melvin and Bren […]
Study tests immunotherapy, chemotherapy combination for HER2-amplified gastric or esophageal cancer

A Hoosier Cancer Research Network study is testing a treatment combination for patients with gastric or esophageal cancer. The phase II study, HCRN GI17-319, focuses on adult patients whose cancer cannot be removed by surgery or has metastasized, and possess an amplification of the gene known as human epidermal growth factor receptor 2 (HER2). The […]
Phase II study tests PARP inhibitor, niraparib, in metastatic esophageal cancer patients with HR, LOH, or germline mutations

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center are leading a multi-site phase II study through the Hoosier Cancer Research Network for previously treated metastatic esophageal cancer patients with specific genetic mutations. The study is now open to accrual at the IU Simon Cancer Center, Moffitt Cancer Center, and Roswell Park […]